Alaska is huge and sparsely populated, with tremendous natural resources. Its isolation would protect you from a social breakdown.
Another potential alternative is the Pacific Northwest, with its temperate temperature, fertile land, and fresh water.
Rocky Mountain climates range from high alpine meadows to deep lowlands. Timber, freshwater, and wildlife abound in them.
The Great Basin is a vast desert from Oregon to Nevada. Many small, isolated villages have long been self-sufficient.
The Ozarks are central US mountains. The area is secluded and rich in freshwater.
Hawaii is a Pacific Ocean archipelago. If you like warm weather and pure water, it's ideal. However, Hawaii's tsunami and storm threats must be considered.
The US island of Puerto Rico is in the Caribbean Sea. It's tropical and has freshwater.